Arginase and glucose-6-phosphate dehydrogenase activities in spontaneous mammary carcinogenesis

Arginase and glucose-6-phosphate dehydrogenase activities in the mammary glands of 4, 8 and 12 month old groups and in precancerous nodules and mammary tumours in (C3H Jax) virgin mice were studied. It was observed that activities of both the enzymes in different age groups of both the strains are comparable, but are significantly lower than those present in precancerous nodules and mammary tumour. Activities of both the enzymes in the precancerous nodules and tumour tissue are comparable.