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Updated: Aug 10, 2026

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Published on: October 24, 2016
Production of beta-(4-hydroxyphenyl)ethanol and beta-(4-hydroxyphenyl)lactic acid by Candida species
Abstract:
Two crystalline compounds were isolated from the culture filtrates of Candida species grown in synthetic medium supplemented with L-tyrosine as the sole source of nitrogen. These compounds were characterized as beta-(4-hydroxyphenyl)ethanol (HOPEA) and beta-(4-hydroxyphenyl)lactic acid (HOPLA). The production of these compounds in five species (both pathogenic and non-pathogenic) was compared and marked differences were revealed. Experiments using L-[14C]tyrosine indicated that both HOPEA and HOPLA are synthesized from L-tyrosine.
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