Neuro-Behcet disease: two cases and neuroradiologic findings

Area of Science:

• Neuroimmunology
• Vascular Neurology

Background:

• Behcet disease is a rare multisystem inflammatory disorder.
• Ocular and mucocutaneous manifestations are hallmark symptoms.

Observation:

• Two Behcet disease patients presented with neurologic deficits preceding characteristic lesions.
• Neurologic symptoms appeared 6-32 weeks before ocular/mucocutaneous signs.

Findings:

• Neuroradiologic studies revealed expanding avascular foci in the basal ganglia.
• These findings suggest infarction secondary to vasculitis affecting the brain.

Implications:

• Highlights the potential for neurologic manifestations to be the initial presentation of Behcet disease.
• Emphasizes the importance of considering Behcet disease in patients with unexplained basal ganglia infarction and vasculitis.