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[Experimental studies in animals concerning adhesive orchiopexy (author's transl)]
Research in Experimental Medicine. Zeitschrift Fur Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie
|March 20, 1978
Abstract:
In an experimental study in rabbits, histoxicity of butyl-2-cyano-acrylic-tissue adhesive for orchiopexy was comapred with the usual suture type fixation of the testis. There was no difference in tissue damage between the two methods in respect to local inflammation, diameters of the tubules and the number of spermatogonic cells. Using several established cell lines, a significant cytotoxicity was seen when dropping butyl-2-cyanoacrylic-adhesive into the tissue cultures. Mutagenic influence of butyl-2-cyanoacrylate should be ruled out in children prior to clinical application. In addition, the high cost of the adhesive should be considered.