Characterization of adenovirus type 12 tumour antigen produced in chick fibroblasts

Tumor (T) antigen was characterized in non-permissive chick fibroblasts and permissive HEp-2 cells infected with Ad12 either in the presence or in the absence of cytosine arabinoside. Antiserum against T antigen specifically immunoprecipitated two polypeptides of apparent mol. wt. 50 000 and 11 000.