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Related Experiment Videos

Periodic alternating gaze.

J D Stewart, T H Kirkham, G Mathieson

    Neurology
    |February 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Periodic alternating gaze deviation, a rare sign of severe brain damage, was observed in a patient with bilateral cerebral infarction. This finding indicates widespread cerebral disease affecting eye movement control.

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    Area of Science:

    • Neurology
    • Neuroscience
    • Ophthalmology

    Background:

    • Periodic alternating gaze deviation is a rare neurological sign.
    • It is typically associated with brainstem or cerebellar lesions.

    Observation:

    • A 77-year-old male patient presented with periodic alternating conjugate horizontal ocular deviation.
    • This symptom persisted for 2 days before resolving shortly before death.
    • Autopsy confirmed bilateral cerebral infarction.

    Findings:

    • The patient's ocular deviation suggests acute bilateral cerebral disease.
    • The phenomenon points to a relatively intact brainstem despite extensive cerebral damage.
    • This case adds to the four previously reported instances of this specific sign.

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    Implications:

    • Periodic alternating gaze deviation can indicate severe, widespread cerebral pathology.
    • This sign may help differentiate between cerebral and brainstem lesions in acute neurological events.
    • Further research is needed to understand the precise mechanisms linking cerebral infarction to this ocular motor abnormality.