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The prevention by creatinol O-phosphate of myocardial lesions evoked by isoprenaline
Archives Internationales De Pharmacodynamie Et De Therapie
|February 1, 1979
Abstract:
Isoprenaline 30 mg/kg has been injected subcutaneously in rats pretreated or not with Creatinol O-phosphate (200 mg/kg intraperitoneously). Isoprenaline-induced cardionecrosis and the associated alterations of the ionic composition of the heart were reduced when Creatinol O-phosphate was injected 4 hr before isoprenaline.