Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Disseminated varicella complicating ulcerative colitis.

J K Keene, D K Lowe, J L Grosfeld

    JAMA
    |January 2, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Inactivation of the bacterial pathogens Staphylococcus pseudintermedius and Acinetobacter baumannii by butanoic acid.

    Journal of applied microbiology·2018
    Same author

    Preface.

    Environmental monitoring and assessment·2013
    Same author

    Transanal endoscopic microsurgery for rectal carcinoids: the largest reported United States experience.

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2011
    Same author

    Strategies to prevent organ failure.

    Current opinion in anaesthesiology·2006
    Same author

    The dental attitudes, knowledge and health practices of patients with Juvenile Idiopathic Arthritis.

    European journal of paediatric dentistry·2006
    Same author

    Reversible intestinal pseudoobstruction associated with neural crest tumors.

    Journal of pediatric gastroenterology and nutrition·2001

    Disseminated varicella is a rare complication in ulcerative colitis patients on steroids. Prophylactic zoster-immunoglobulin is recommended for exposed patients to prevent severe varicella infection.

    Area of Science:

    • Immunology
    • Gastroenterology
    • Infectious Diseases

    Background:

    • Ulcerative colitis (UC) management frequently involves immunosuppressive therapies, particularly corticosteroids.
    • Patients with inflammatory bowel disease, including UC, may have altered immune responses.
    • Disseminated varicella (chickenpox) is an uncommon but serious complication in immunocompromised individuals.

    Observation:

    • A fatal case of disseminated varicella infection was documented in a patient with a history of ulcerative colitis.
    • The patient was undergoing treatment with steroid therapy at the time of varicella infection.

    Findings:

    • The occurrence of fatal varicella in an ulcerative colitis patient on steroids highlights a significant clinical risk.
    • This case underscores the potential severity of varicella-zoster virus reactivation or primary infection in this patient population.

    Related Experiment Videos

    Implications:

    • Administration of zoster-immunoglobulin (passive immunization) should be considered for ulcerative colitis patients exposed to varicella.
    • Proactive prophylactic measures are crucial for managing varicella exposure risks in steroid-treated UC patients.
    • Further research into optimal varicella prevention strategies for immunocompromised IBD patients is warranted.