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Updated: Feb 18, 2026

Pre-Conditioning the Airways of Mice with Bleomycin Increases the Efficiency of Orthotopic Lung Cancer Cell Engraftment
Published on: June 28, 2018
[Chemotherapeutic problems in surgically treated bronchial carcinomas (author's transl)]
Abstract:
There is a report about experiences of a combined surgical and chemotherapeutical therapy with 765 resected patients who had suffered from a bronchial neoplasms. 80 patients had been radically resected and treated with chemotherapy. From 235 palliatively resected persons 124 received cyclophosphamid- or trenimon-therapy after the operation. The 5 years-survival rate of the radically resected persons arose from 50,9 to 58,9% by chemotherapy. In view of the palliatively resected patients the results of 5 years-survival got worse by adjuvant chemotherapy alone or in combination with radiation. But the 3 years-survival results show better relations than the patients without adjuvant therapy. Bronchial stump fistula and empyema as well as other postoperative complications didn't arise by chemotherapy.
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