[Ultrastructure of the bone marrow cells after 85Sr incorporation]

Ultrastructural manifestations of the reaction of the rat bone marrow cells to incorporation of the osteotropic isotope 85Sr in doses of 15 and 150 muCi/100 g of body weight were studied in the electron microscope. It was found that ultrastructures were affected mostly in unidentifiable, blast cells and cells from the reproduction-maturation pool of the myeloid and erythroid series as well as lymphocytes. The lesions consisted in focal cchanges of chromatin and interchromatin structures of the nucleus, nuclear envelope membranes, nucleoli, mitochondrial membranes, endoplasmic reticulum, and plasma membrane. The dynamics of these changes in relation to the time of exposure and irradiation dose were followed.