Related Experiment Videos
Abnormalities of the urinary tract in association with congenital cardiovascular disease
Insights
Congenital cardiovascular disease in children rarely co-occurs with significant urinary tract abnormalities. Most identified anomalies were minor, with no increased incidence of common renal anomalies compared to controls.
Area of Science:
- Pediatric Cardiology
- Urology
- Medical Imaging
Background:
- Congenital cardiovascular disease (CVD) is common in infants and children.
- Urinary tract abnormalities can occur in children, and their association with CVD requires investigation.
Purpose of the Study:
- To determine the incidence of urinary tract abnormalities in children with congenital cardiovascular disease.
- To compare the occurrence of specific renal anomalies in children with and without CVD.
Main Methods:
- Retrospective analysis of abdominal roentgenograms from angiocardiographic studies in children with congenital cardiovascular disease.
- Assessment of urinary tracts in 421 pediatric patients, including those evaluated at autopsy.
- Comparison of renal anomaly incidence with a control group without cardiovascular disease.
Main Results:
- Approximately 2% of children with congenital cardiovascular disease had serious urinary tract disease.
- Approximately 3.5% had clinically insignificant urinary tract anomalies.
- No significant difference in the incidence of bifid collecting system, rotated kidney, horseshoe kidney, or ectopic kidney was found between groups.
Conclusions:
- Serious urinary tract disease is uncommon in children with congenital cardiovascular disease.
- The incidence of common renal anomalies is similar in children with and without congenital cardiovascular disease.
Abstract:
The incidence of urinary tract abnormalities in a group of infants and children with congenital cardiovascular disease was determined by assessing roentgenograms of the abdomen taken following angiocardiographic studies. The urinary tracts of 400 of these patients were so outlined, but in 50 others the tracts could not be outlined. In 21 of the latter the urinary tracts were assessed at autopsy.Of these 421 children, nine (approximately 2%) had serious urinary tract disease, and 15 (approximately 3.5%) had anomalies which were of no clinical significance.The incidence of four renal anomalies-bifid collecting system, rotated kidney, horsehoe kidney and ectopic kidney-was compared with that in another group of patients without cardiovascular disease. No significant difference was found in the incidence of these four anomalies in the two groups.