Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Insulin release in hyperuricemic patients.

U Butturini, C Coscelli, I Zavaroni

    Acta Diabetologica Latina
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Claimed effects, outcome variables and methods of measurement for health claims proposed under regulation (EC) 1924/2006 and related to cognitive function in adults.

    Archives italiennes de biologie·2018
    Same author

    Claimed effects, outcome variables and methods of measurement for health claims proposed under European Community Regulation 1924/2006 in the framework of protection against oxidative damage and cardiovascular health.

    Nutrition, metabolism, and cardiovascular diseases : NMCD·2017
    Same author

    Multivariate prediction of subcutaneous glucose concentration in type 1 diabetes patients based on support vector regression.

    IEEE journal of biomedical and health informatics·2012
    Same author

    Women show worse control of type 2 diabetes and cardiovascular disease risk factors than men: results from the MIND.IT Study Group of the Italian Society of Diabetology.

    Nutrition, metabolism, and cardiovascular diseases : NMCD·2012
    Same author

    Macrophage polarization: the answer to the diet/inflammation conundrum?

    Nutrition, metabolism, and cardiovascular diseases : NMCD·2012
    Same author

    Lower endothelial progenitor cell number, family history of cardiovascular disease and reduced HDL-cholesterol levels are associated with shorter leukocyte telomere length in healthy young adults.

    Nutrition, metabolism, and cardiovascular diseases : NMCD·2011
    Same journal

    Serum lipids, microalbuminuria and metabolic control in diabetic children.

    Acta diabetologica latina·1991
    Same journal

    Factors for development of secondary failure to sulfonylurea drugs in non-insulin-dependent diabetes mellitus.

    Acta diabetologica latina·1991
    Same journal

    The effects of bilio-jejunal diversion on streptozotocin diabetes in the rat.

    Acta diabetologica latina·1991
    Same journal

    Plasma lipoproteins and apolipoproteins in insulin-dependent and young non-insulin-dependent Arab women.

    Acta diabetologica latina·1991
    Same journal

    Anthropometric studies in diabetes in the Tropics.

    Acta diabetologica latina·1991
    Same journal

    Insulin requirement of simple and complex carbohydrate foods in type 1 (insulin-dependent) CSII-treated diabetic subjects, obtained by biostator. Correlation with glycaemic index.

    Acta diabetologica latina·1991
    See all related articles

    Hyperuricemic individuals show an enhanced insulin response to glucose and tolbutamide, suggesting a complex metabolic link between carbohydrate and purine metabolism.

    Area of Science:

    • Endocrinology
    • Metabolic Research
    • Clinical Biochemistry

    Background:

    • Hyperuricemia is associated with metabolic disturbances.
    • Understanding the insulin response in hyperuricemia is crucial for metabolic health.

    Purpose of the Study:

    • To investigate the insulin response to oral glucose and intravenous tolbutamide in hyperuricemic subjects compared to controls.
    • To explore the relationship between hyperuricemia, glucose tolerance, and insulin secretion.

    Main Methods:

    • Studied insulin response to oral glucose and intravenous tolbutamide in hyperuricemic and control groups.
    • Assessed glucose tolerance and insulin levels (IRI) after stimuli.

    Main Results:

    • Impaired glucose tolerance was observed only in obese hyperuricemic subjects.

    Related Experiment Videos

  • Hyperuricemic subjects exhibited an enhanced insulin response to oral glucose.
  • Intravenous tolbutamide and fructose led to significantly higher insulin increases in hyperuricemic subjects.

    • Conclusions:

    • The insulin response abnormalities in hyperuricemia are complex and not solely explained by obesity or uric acid levels.
    • A potential interplay between carbohydrate and purine metabolism may underlie the observed insulin response patterns.