Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Alpha-thalassemia.

J G Adams, M H Steinberg

American Journal of Hematology

|January 1, 1977

Summary

This summary is machine-generated.

This review covers alpha-thalassemia, detailing its incidence, genetics, clinical features, and diagnosis. It also explores potential clinical uses of alpha-thalassemia molecular biology.

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

HbF/F-cell and the Phenotype of Sickle Cell Disease.

medRxiv : the preprint server for health sciences·2026

Same author

Mutations in the β-globin gene from a Saudi population: an update.

International journal of laboratory hematology·2016

Same author

BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia.

Blood cells, molecules & diseases·2015

Same author

Quantitative MRI analysis of craniofacial bone marrow in patients with sickle cell disease.

AJNR. American journal of neuroradiology·2012

Same author

Clinical and radiologic findings of inner ear involvement in sickle cell disease.

AJNR. American journal of neuroradiology·2011

Same author

Healing of Pseudointimas in Velour-lined, Impermeable Arterial Prostheses.

The American journal of pathology·2009

Same journal

Signaling Mutations Negate the Favorable Impact of NPM1 Mutations in Older Patients With Newly Diagnosed Acute Myeloid Leukemia Treated With VEN/HMA.

American journal of hematology·2026

Same journal

Comparative Efficacy of Intranasal, Intramuscular, and Intravenous Vitamin B12 Therapy for Hematological Recovery in Vitamin B12 Deficiency Anemia: A Randomized Controlled Trial.

American journal of hematology·2026

Same journal

Clinical Predictors of Response in Chronic Graft-Versus-Host Disease: Results From the "Predicting the Quality of Response to Specific Treatments (PQRST)" Trial.

American journal of hematology·2026

Same journal

Relapse Thresholds (12/24 Mo) Define Survival Disparity in Pediatric B-ALL.

American journal of hematology·2026

Same journal

Quizartinib in Combination With FLAG-IDA for Relapsed or Refractory Acute Myeloid Leukemia (FLAG-QUIDA): A PETHEMA Phase I-II Trial.

American journal of hematology·2026

Same journal

Defining a Subgroup of Myelodysplastic Syndrome Patients With Very Poor-Risk Cytogenetics Demonstrating a Relatively More Favorable Outcome After Allogeneic Hematopoietic Cell Transplantation.

American journal of hematology·2026

See all related articles

Area of Science:

Genetics
Hematology
Molecular Biology

Background:

Alpha-thalassemia is a common inherited blood disorder.
Understanding its molecular basis is crucial for diagnosis and management.

Purpose of the Study:

To review current knowledge on alpha-thalassemia.
To discuss the clinical applications of its molecular biology.

Main Methods:

Literature review of existing studies on alpha-thalassemia.
Analysis of genetic and clinical data.
Exploration of molecular biology findings.

Main Results:

Comprehensive overview of alpha-thalassemia's incidence, genetics, clinical spectrum, and diagnostic methods.
Discussion on the potential clinical utility of molecular insights.

Conclusions:

Current understanding of alpha-thalassemia is well-established.
Molecular biology offers promising avenues for future clinical applications in managing alpha-thalassemia.