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Aggressive chondroblastoma. Report of a case with multiple bone and soft tissue involvement
Clinical Orthopaedics and Related Research
|July 1, 1977
Summary
A recurrent chondroblastoma in a 14-year-old showed aggressive features. Elevated mitotic rates in recurrent tumors may indicate a propensity for aggressive behavior in chondroblastomas.
Area of Science:
- Orthopedic Oncology
- Skeletal Pathology
Background:
- Chondroblastoma is a rare bone tumor typically presenting with benign histologic features.
- Recurrent chondroblastomas, particularly with extraosseous involvement, raise concerns for aggressive behavior.
Observation:
- A 14-year-old male presented with a recurrent chondroblastoma involving the talus, calcaneus, and ankle soft tissues.
- The recurrent tumor and associated soft tissue nodules exhibited a significantly elevated mitotic rate compared to the initial lesion.
Findings:
- The elevated mitotic rate in the recurrent chondroblastoma suggests an aggressive variant.
- Histologic appearance alone may not reliably predict the biologic behavior of chondroblastomas.
Implications:
- Objective quantitation of cytologic features, such as mitotic rate, can help identify chondroblastomas with aggressive potential.
- Recognizing aggressive variants is crucial for appropriate treatment and patient management of chondroblastoma.