[SKF 28,175: preliminary study of a new antidepressant]

This is a preliminary report concerning a new antidepressant, SKF 28,175 which is neither an IMAO nor does it have the usual tricyclic structure, retaining the CF 3 at the number two position on the ring. It was studied in 27 male and female patients. The drug was highly effective, within 4-7 days for the most part, as confirmed by statistical analysis of the Hamilton Rating Scale. There were relatively few side effects. Only one dosage per day, in the evening, was required.