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Related Experiment Videos

Recent experience with the Baylor left ventricular bypass pump.

J E Chimoskey, W O'Bannon, J R Cant

    Biomaterials, Medical Devices, and Artificial Organs
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

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    The Baylor left ventricular assist device, a pneumatic diaphragm pump, shows potential for short-term cardiac support. Redesign efforts focus on preventing thrombus formation at critical junctions and valve seats.

    Area of Science:

    • Biomedical Engineering
    • Cardiovascular Devices
    • Medical Device Design

    Background:

    • The Baylor left ventricular bypass pump utilizes a pneumatically actuated diaphragm with a segmented polyurethane lining.
    • Its swirl design promotes circular blood flow, featuring tilting disc inflow and outflow valves with a 60 ml stroke volume.

    Purpose of the Study:

    • To evaluate the performance and identify areas for improvement in the current Baylor left ventricular bypass pump design.
    • To address thrombus formation issues observed in preclinical trials.

    Main Methods:

    • Preclinical implantation of eighteen devices in normal calves.
    • Monitoring pump operation duration and identifying sites of thrombus formation.

    Main Results:

    Related Experiment Videos

    • The device was implanted in eighteen calves, with a mean operation duration of eleven days.
    • Thrombus formation was observed at pump-canula junctions and valve seat regions.

    Conclusions:

    • The Baylor left ventricular bypass pump is suitable for short-term use (up to 14 days) in preclinical models.
    • Ongoing redesign aims to mitigate thrombus formation by optimizing flow dynamics and eliminating stagnation zones.