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Xanthine oxidase induced depolymerization of hyaluronic acid in the presence of ferritin
FEBS Letters
|November 5, 1984
Abstract:
Oxygen free radicals generated by xanthine oxidase are able to depolymerize hyaluronic acid in the presence of ferritin-bound iron. This suggests that ferritin can catalyse the Haber-Weiss reaction, leading to the formation of highly damaging hydroxyl radicals.