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[Relation between calcium phosphates and calcium oxalates in urinary calculi]
Summary
This review covers calcium phosphate and calcium oxalate precipitation in urinary stones. Simultaneous presence often results from one mineral nucleating homogeneously, followed by the other nucleating heterogeneously.
Area of Science:
- Biochemistry
- Materials Science
Context:
- Urinary stones frequently contain calcium phosphates and calcium oxalates.
- Understanding the precipitation mechanisms is crucial for stone prevention and treatment.
Purpose:
- To review the current knowledge on the precipitation of calcium phosphates and calcium oxalates.
- To elucidate the nucleation pathways leading to the simultaneous presence of these minerals in urinary stones.
Summary:
- The review discusses the precipitation processes of calcium phosphates and calcium oxalates.
- Experimental conditions can lead to homogeneous nucleation of one mineral, followed by heterogeneous nucleation of the other, explaining their co-occurrence in stones.
Impact:
- Provides insights into the formation mechanisms of complex urinary calculi.
- Informs the development of targeted strategies for preventing and managing calcium-based urinary stones.