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Liver affection associated with Yersinia enterocolitica infection
Acta Chirurgica Scandinavica
|January 1, 1977
Summary
Yersinia enterocolitica infection can mimic gallbladder issues like cholecystitis. This bacterium may cause chronic, relapsing liver conditions with elevated liver enzymes and bilirubin.
Area of Science:
- Gastroenterology
- Hepatology
- Infectious Diseases
Background:
- Yersinia enterocolitica is a known pathogen causing various clinical symptoms.
- Mesenteric lymphadenitis and terminal ileitis are common presentations, often termed 'right iliac fossa syndrome'.
- The spectrum of Yersinia enterocolitica infections may extend to hepatic manifestations.
Observation:
- Two cases of liver affection associated with positive Yersinia enterocolitica antibody titres are presented.
- Clinical presentation mimicked cholecystitis with elevated liver enzymes (ASAT, LD, AP) and bilirubin.
- The condition demonstrated a potential for chronic, relapsing disease course.
Findings:
- Case 1: Chronic relapsing liver affection with a stable Yersinia enterocolitica antibody titre.
- Case 2: Acute Australia antigen-negative hepatitis with fluctuating antibody titres.
- Elevated liver function tests and bilirubin levels were noted in association with Yersinia infection.
Implications:
- Yersinia enterocolitica should be considered in the differential diagnosis of cholecystitis-like symptoms.
- The bacterium may be implicated in chronic or relapsing liver diseases.
- Further investigation into Yersinia-associated hepatitis is warranted.