[Effectiveness of sympathoadrenergic blocking in prevention of postoperative acute pancreatitis]

The role of the vascular factor (namely hypoperfusion) in the onset of pancreatic necrosis is a well-established fact. In the present study an analysis is made of the efficiency of drug blocking of alpha and beta adreno-receptors in the prophylaxis of acute postoperative pancreatitis, following surgery of the Oddi sphincter. Compared with a control group of 301 papillo-sphincterotomies performed in a previous period the application of adrenergic blocking in 127 patients in whom interventions were performed on the Oddi sphincter led to a significant reduction in both morbidity and mortality through acute postoperative pancreatitis, from 5 to 2,3%, and from 1,3 to 0,7% respectively.