[beta-Cell residual function in juvenile diabetes mellitus (author's transl)]

Estimation of C-peptide (IRCP) can be used to measure the residual beta-cell function in insulin treated diabetics. IRCP was estimated in 46 juvenile diabetics. A significant correlation between basal IRCP-levels and duration of diabetes as well as daily insulin requirement could be shown. There was no linear correlation between glucosuria and IRCP. However, patients with IRCP > 1,0 ng/ml had significantly lower glucosuria ( p < 0,005). Endogenous residual function of the beta-cells seems to be of importance for metabolic control in diabetic children.