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Familial occurrence of tardive dyskinesia
Abstract:
Tardive dyskinesia remains a poorly understood consequence of neuroleptic treatment for psychiatric illness. To date, there have been no reports in the literature regarding the presence of dyskinetic symptomatology in first degree relatives or other family members. The following two cases reveal the development of abnormal involuntary movement in brothers with similar mental illness and treatment histories, and suggest the importance of examining neuroleptically treated relatives of an affected individual for dyskinesia and may suggest a genetic factor in vulnerability.
Insights
Tardive dyskinesia, a movement disorder from antipsychotic drugs, was observed in two brothers with similar psychiatric conditions. This suggests a potential genetic link and the need to screen family members for this condition.
Area of Science:
- Neuroscience
- Psychiatry
- Genetics
Background:
- Tardive dyskinesia is a complex neurological disorder.
- Its etiology is not fully understood.
- No prior studies have investigated familial links.