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Comparison of multiple puncture liquid tuberculin test with Mantoux test
Lancet (London, England)
|March 28, 1981
Summary
The Imotest, a disposable tuberculin skin test, is comparable to the traditional Mantoux test for identifying tuberculosis reactors. Its ease of use and accurate results make it a viable option for large-scale tuberculosis screening programs.
Area of Science:
- Immunology
- Infectious Diseases
- Public Health
Background:
- Tuberculosis (TB) screening relies on accurate skin testing.
- The Mantoux test is a standard but can be labor-intensive.
- Alternative methods are sought for efficient TB detection.
Purpose of the Study:
- To compare the efficacy of the disposable Imotest with the conventional Mantoux test.
- To evaluate the accuracy and reliability of Imotest for tuberculin reactivity.
- To assess Imotest's suitability for large-scale population screening.
Main Methods:
- Two comparative studies were conducted using Imotest and Mantoux tests.
- Tuberculin reactors were identified using conventional and maximum likelihood techniques.
- Test readings were analyzed at 48 and 72 hours post-administration.
Main Results:
- The second study demonstrated comparable performance between Imotest and Mantoux tests in identifying true TB reactors.
- A significant difference in reaction readings was observed between 48 and 72 hours for both tests.
- Maximum likelihood technique provided a more precise estimation of false reaction rates.
Conclusions:
- Imotest shows comparable tuberculin selectivity to the Mantoux method.
- The disposable Imotest is an acceptable and easy-to-read alternative for TB screening.
- Imotest is particularly suitable for screening large populations due to its efficiency.