Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Febrile convulsions and cot death.

R Sunderland, J L Emery

    Lancet (London, England)
    |July 25, 1981
    PubMed
    Summary

    Febrile convulsions and some sudden infant deaths may share a common cause, possibly thermolabile syncope. Age at occurrence influences whether a febrile stimulus results in a convulsion or death.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The need for Paediatric Emergency Laparotomy Audit (PELA) in the UK.

    Annals of the Royal College of Surgeons of England·2019
    Same author

    Platelets loaded with liposome-encapsulated thrombin have increased coagulability.

    Journal of thrombosis and haemostasis : JTH·2018
    Same author

    Pulmonary Embolism in Children.

    Archives of disease in childhood·2010
    Same author

    With commentary.

    Archives of disease in childhood·2010
    Same author

    C-reactive protein as a predictor of outcome after discharge from the intensive care: a prospective observational study.

    British journal of anaesthesia·2010
    Same author

    Erythroblastosis foetalis and breast-feeding.

    British medical journal·2010

    Area of Science:

    • Pediatrics
    • Neurology
    • Public Health

    Background:

    • Sudden unexpected infant death (SUID), often termed 'cot death', and febrile convulsions are significant pediatric concerns.
    • Understanding the potential links between these events is crucial for diagnosis and prevention.

    Purpose of the Study:

    • To investigate the relationship between febrile convulsions and cot deaths in young children.
    • To explore potential shared etiological factors and age-related differences in presentation.

    Main Methods:

    • Retrospective analysis of hospital admission and death records for children under two years old in Sheffield (1975-1979).
    • Examination of rectal temperatures in cases of cot death prior to refrigeration.
    • Comparison of age at presentation for both conditions.

    Main Results:

    • Identified 475 first-time febrile convulsions and 50 cot deaths among 40,544 children.
    • Elevated rectal temperatures (above 38°C and 40°C) were noted in a subset of cot death cases.
    • Cot deaths predominantly occurred before six months, while febrile convulsions were more common after this age.

    Conclusions:

    • Febrile convulsions and some cot deaths may represent different outcomes of a similar response to a febrile stimulus, influenced by age.
    • Thermolabile syncope is proposed as a potential common mechanism, leading to cerebral ischemia in younger infants.
    • Prompt rectal temperature measurement in cot death cases is recommended; vagally mediated reflex aberrations may also play a role.

    Related Experiment Videos