Protein synthesis in pig kidney cells infected with herpes simplex virus type 1

Two polypeptides of apparent mol. mass 87,000 and 35,000 were identified in pig kidney cells infected with herpes simplex virus type 1 (HSV-1) after reversing the cycloheximide block. The synthesis of the polypeptide 87,000 declined from 22 hr post infection (p.i.). Its production was prevented by actinomycin D added to the infected cells after removal of cycloheximide. Evidence is presented that the polypeptide 35,000 may be of the cellular origin.