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[Isolation and identification of antigen-specific T-cell-receptors (author's transl)]
Experimental allergic encephalomyelitis was induced by injection of myelin basic protein into guinea pigs strain 13. Specific antigen binding T-cell receptors were isolated by means of a nylon net coupled with antigen. A phage immunoassay was set up as an analytical tool for detection of the receptors. They were found not to be identical with common immunoglobulins and have a molecular weight of 71,000.
Experimental allergic encephalomyelitis was induced by injection of myelin basic protein into guinea pigs strain 13. Specific antigen binding T-cell receptors were isolated by means of a nylon net coupled with antigen. A phage immunoassay was set up as an analytical tool for detection of the receptors. They were found not to be identical with common immunoglobulins and have a molecular weight of 71,000.