Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Aspirin and human sleep.

J A Horne, J E Percival, J R Traynor

    Electroencephalography and Clinical Neurophysiology
    |August 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Aspirin intake significantly reduced slow-wave sleep and increased stage 2 sleep in women. This common pain reliever also disrupted sleep continuity during and after administration.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Themed section.

    British journal of pharmacology·2014
    Same author

    Pyrrolo- and pyridomorphinans: non-selective opioid antagonists and delta opioid agonists/mu opioid partial agonists.

    Bioorganic & medicinal chemistry·2014
    Same author

    The Concise Guide to PHARMACOLOGY 2013/14: overview.

    British journal of pharmacology·2014
    Same author

    Positive allosteric modulators of the μ-opioid receptor: a novel approach for future pain medications.

    British journal of pharmacology·2014
    Same author

    Sleep restriction and serving accuracy in performance tennis players, and effects of caffeine.

    Physiology & behavior·2013
    Same author

    'Post-lunch' sleepiness during prolonged, monotonous driving - effects of meal size.

    Physiology & behavior·2011
    Same journal

    Coming to terms with brain waves.

    Electroencephalography and clinical neurophysiology·2014
    Same journal

    Habituation of lower leg stretch responses in Parkinson's disease.

    Electroencephalography and clinical neurophysiology·2000
    Same journal

    Asymmetry of cortical excitability revealed by transcranial stimulation in a patient with focal motor epilepsy and cortical myoclonus.

    Electroencephalography and clinical neurophysiology·2000
    Same journal

    Evoked isometric muscle contractions in myopathies: analysis of pathophysiological properties by different stimulus patterns.

    Electroencephalography and clinical neurophysiology·2000
    Same journal

    Task-related coherence and task-related spectral power changes during sequential finger movements.

    Electroencephalography and clinical neurophysiology·2000
    Same journal

    Electrophysiological studies in mild idiopathic carpal tunnel syndrome.

    Electroencephalography and clinical neurophysiology·2000
    See all related articles

    Area of Science:

    • Pharmacology
    • Sleep Science
    • Neuroscience

    Background:

    • Aspirin is a widely used nonsteroidal anti-inflammatory drug (NSAID).
    • Sleep disturbances are common and impact overall health.
    • The effects of aspirin on sleep architecture are not fully understood.

    Purpose of the Study:

    • To investigate the impact of daily aspirin administration on human sleep patterns.
    • To assess changes in specific sleep stages and sleep continuity.

    Main Methods:

    • A double-blind study involving two groups of 8 female participants.
    • Participants received either 1800 mg of aspirin or a placebo daily for 4 days.
    • Polysomnography was used to monitor sleep stages and continuity.

    Related Experiment Videos

    Main Results:

    • Aspirin significantly decreased slow-wave sleep duration.
    • Stage 2 sleep was significantly increased in the aspirin group.
    • Intra-subject night-to-night continuity of several sleep stages was disrupted by aspirin during both drug and recovery periods.

    Conclusions:

    • Daily aspirin intake can alter sleep architecture in women.
    • The findings suggest potential implications for individuals using aspirin regularly.
    • Further research is warranted to explore the mechanisms and long-term effects.