Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The refurbished pulse generator.

H Mond, S Tartaglia, A Cole

    Pacing and Clinical Electrophysiology : PACE
    |May 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Use of point-of-care ultrasound in the diagnosis of uterine rupture.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2026
    Same author

    The environmental impact of intravenous antimicrobial therapies: a comparison of OPAT and in-patient administration care pathways-right-to-reply.

    JAC-antimicrobial resistance·2025
    Same author

    Patient-reported outcomes following surgery for adolescent idiopathic scoliosis performed in adolescence versus adulthood.

    Annals of the Royal College of Surgeons of England·2024
    Same author

    Staff Perceptions on the Effectiveness of GRiP-S, a New Approach to Clinical Supervision Incorporating Safewards: An Interpretive Phenomenological Analysis.

    Issues in mental health nursing·2024
    Same author

    A potential biomarker of radiosensitivity in metastatic hormone sensitive prostate cancer patients treated with combination external beam radiotherapy and radium-223.

    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2023
    Same author

    First Dark Matter Search Results from the LUX-ZEPLIN (LZ) Experiment.

    Physical review letters·2023
    Same journal

    A Case of Permanent Pacemaker Implantation via the Epicardial Approach Using the 3830 Lead in an 11-Day-Old Neonate (With Follow-Up of the Above Case).

    Pacing and clinical electrophysiology : PACE·2026
    Same journal

    Cryoballoon Versus Radiofrequency Ablation for Persistent Atrial Fibrillation: Meta-Analysis of Randomized Trials.

    Pacing and clinical electrophysiology : PACE·2026
    Same journal

    Tilt Test Duration in Suspected Vasovagal Syncope: Temporal Patterns and Diagnostic Yield in Patients From Central China.

    Pacing and clinical electrophysiology : PACE·2026
    Same journal

    Combined Leadless Pacing and Subcutaneous ICD Therapy in Long QT Syndromes.

    Pacing and clinical electrophysiology : PACE·2026
    Same journal

    Association of Anesthesia Modality With Procedural Parameters and Clinical Outcomes in PVI for Atrial Fibrillation.

    Pacing and clinical electrophysiology : PACE·2026
    Same journal

    Zero-Fluoroscopy Cryoballoon Ablation for Paroxysmal Atrial Fibrillation in a Patient With Dextrocardia: A Case Report.

    Pacing and clinical electrophysiology : PACE·2026
    See all related articles

    Refurbishing long-life lithium pulse generators for re-implantation is a safe and economical procedure. This practice, involving thorough cleaning and sterilization, proved effective in reducing waste and costs associated with pacemakers.

    Area of Science:

    • Biomedical Engineering
    • Medical Device Reprocessing
    • Cardiology

    Background:

    • Long-life lithium pulse generators, functional for over five years, are often removed from patients.
    • Pulse generator refurbishing is common globally but not widely adopted in the United States.
    • Reprocessing reusable medical devices is crucial for cost-effectiveness and sustainability.

    Purpose of the Study:

    • To evaluate the safety and economic viability of refurbishing explanted lithium pulse generators for re-implantation.
    • To assess the complication rates and overall success of refurbished pulse generators.
    • To determine the feasibility of implementing a standardized refurbishing protocol.

    Main Methods:

    • Explanted lithium pulse generators were cleaned with a quaternary ammonium compound and formaldehyde.

    Related Experiment Videos

  • Generators underwent electronic testing; functional units were sterilized using distilled water and ethylene oxide gas.
  • A cohort of 600 pulse generators were implanted, with 93 removed and 83 (89%) refurbished over 48 months.
  • Main Results:

    • Eighty-three percent of removed pulse generators were successfully refurbished and made available for re-implantation.
    • Only two complications were reported in patients receiving refurbished devices: one instance of infection spread and one removal due to power depletion.
    • No primary infections or unusual tissue reactions were observed, indicating the sterilization process was effective.

    Conclusions:

    • The described pulse generator refurbishing protocol is a safe and economical procedure.
    • Reprocessing functional explanted pulse generators can significantly reduce medical device waste and healthcare costs.
    • This practice offers a viable alternative to discarding fully functional, long-life pulse generators.