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Updated: Aug 13, 2026

Preparation of Pancreatic Acinar Cells for the Purpose of Calcium Imaging, Cell Injury Measurements, and Adenoviral Infection
10:39

Preparation of Pancreatic Acinar Cells for the Purpose of Calcium Imaging, Cell Injury Measurements, and Adenoviral Infection

Published on: July 5, 2013

[Examination of pancreatic function in children with special reference to the PABA-test (author's transl)]

G Dockter, F C Sitzmann

    Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
    |December 1, 1980
    PubMed

    Insights

    Accurate diagnosis of pancreatitis relies on lipase and trypsin tests over amylase. Fecal tests like PABA and PLT aid in assessing pancreatic function, especially in chronic conditions and cystic fibrosis.

    Area of Science:

    • * Gastroenterology and Clinical Diagnostics
    • * Biochemical markers for pancreatic exocrine function

    Context:

    • * Diagnostic challenges in acute and chronic pancreatitis.
    • * Limitations of traditional amylase testing.
    • * Emerging role of lipase and trypsin assays.

    Purpose:

    • * To evaluate the utility of various diagnostic markers for pancreatic diseases.
    • * To compare the effectiveness of serum and fecal-based tests.
    • * To assess the role of newer screening procedures.

    Summary:

    • * Serum lipase and radio-immunoreactive trypsin are more effective than amylase for diagnosing acute pancreatitis.
    • * Fecal tests, including PABA-test and pancreolauryl-test (PLT), offer semiquantitative assessment of pancreatic secretory function.
    • * These fecal tests are valuable for monitoring cystic fibrosis and Shwachman-syndrome, while older methods like fat quantification are obsolete.

    Impact:

    • * Improved diagnostic accuracy for acute and chronic pancreatitis.
    • * Enhanced monitoring of pancreatic exocrine function in specific pediatric and iatrogenic conditions.
    • * Guidance on selecting appropriate diagnostic and monitoring tools for pancreatic insufficiency.

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