Related Experiment Videos
Classification of cardioactive drugs in vivo by using programmed electrical stimulation in combination with
Acta Medica Scandinavica. Supplementum
|January 1, 1981
Abstract:
The effect of antiarrhythmic drugs on myocardial refractoriness may be due to changes either in Vmax of phase 0 or the phase of repolarization of the AP or both. By using programmed electrical stimulation in combination with MAP recordings at different pacing rates in the intact dog heart, it was possible to classify and to a certain extent to elucidate the mode of action of various cardioactive drugs in vivo.