Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Free-living amebic meningoencephalitides: comparative study.

A J Martínez

    Neurologia, Neurocirugia, Psiquiatria
    |January 1, 1977
    PubMed
    Summary

    Primary amebic meningoencephalitis (PAM) caused by Naegleria is acute and fatal, while Acanthamoeba causes a chronic form. Differentiating these central nervous system infections is crucial for diagnosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Dissipative Landau-Zener tunneling in the crossover regime from weak to strong environment coupling.

    Nature communications·2025
    Same author

    <i>Bocconia frutescens</i> L. induces neurological defects in rat offspring.

    Journal of developmental origins of health and disease·2024
    Same author

    Search for CP violation in B0-B0 mixing using partial reconstruction of B0→D*- Xℓ+ νℓ and a kaon tag.

    Physical review letters·2014
    Same author

    Therapeutic perspectives of epigenetically active nutrients.

    British journal of pharmacology·2014
    Same author

    Organochlorine pesticide level differences among female inhabitants from Veracruz, Puebla and Tabasco, Mexico.

    Bulletin of environmental contamination and toxicology·2014
    Same author

    Measurement of the D*(2010)+ meson width and the D*(2010)+ - D0 mass difference.

    Physical review letters·2013

    Area of Science:

    • Neurology
    • Infectious Diseases
    • Parasitology

    Background:

    • Primary amebic meningoencephalitis (PAM) affects the central nervous system (CNS).
    • Caused by free-living ameboflagellates: Naegleria (N) and Acanthamoeba (A).
    • Distinct clinical presentations necessitate differential diagnosis.

    Purpose of the Study:

    • To compare and contrast Naegleria and Acanthamoeba infections of the CNS.
    • To highlight key differences in pathogenesis, clinical presentation, and diagnosis.

    Main Methods:

    • Comparative analysis of clinical and pathological features.
    • Review of case presentations and etiological agents.

    Main Results:

    • Naegleria causes acute, fulminant, hemorrhagic-necrotizing meningoencephalitis with a 3-7 day incubation period, typically in young individuals after water exposure.
    • Acanthamoeba causes subacute/chronic granulomatous meningoencephalitis, often in debilitated individuals, with an unknown incubation period and hematogenous spread.
    • Naegleria infections show trophozoites in lesions; Acanthamoeba infections can have cysts and trophozoites.

    Conclusions:

    • Naegleria and Acanthamoeba infections represent distinct clinico-pathological entities.
    • Understanding these differences is vital for accurate diagnosis of amebic meningoencephalitis.

    Related Experiment Videos