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Related Experiment Videos

Histoplasma meningitis with common variable hypogammaglobulinemia.

J R Couch, D A Romyg

    Neurologia, Neurocirugia, Psiquiatria
    |January 1, 1977
    PubMed
    Summary

    This case study details a rare instance of Histoplasma meningitis in a patient with common variable hypogammaglobulinemia. The successful treatment with amphotericin B highlights a primary central nervous system infection by Histoplasma.

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    Area of Science:

    • Infectious Diseases
    • Neurology
    • Immunology

    Background:

    • Histoplasma meningitis (HM) typically presents with disseminated histoplasmosis (DH).
    • Primary central nervous system (CNS) infections by Histoplasma are uncommon.
    • Common variable hypogammaglobulinemia (CVH) impairs humoral immunity, increasing susceptibility to infections.