[Factors of a nucleic nature in human blood plasma]

Total amount of nucleic acids, content of RNA and RNAase activity were measured in blood plasma of healthy persons and of patients with chronic lympholeukosis. Content of nucleic acids and RNA was increased in blood plasma of these patients as compared with normal persons. Polyribonucleotide from blood plasma exhibited several specific physico-chemical properties: it was resistant to the effect of pancreatic RNAase and had specific nucleotide composition. The RNAase activity in blood plasma of patients with chronic lympholeukosis was similar to the values found in blood of healthy persons.