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Updated: Aug 16, 2026

Subculture and Cryopreservation of Esophageal Adenocarcinoma Organoids: Pros and Cons for Single Cell Digestion
Published on: July 6, 2022
Abstract:
Among 2400 malignant tumors of the gastrointestinal tract, in 12 tumors (11 gastric and 1 jejunal) having the structure of solid cancer, argyrophil cells constituted the basis of the tumor tissue. Argyrophil cell carcinomas were frequently of the saucer-like shape, their microscopic picture combined the features of intestinal carcinoids and oat-cell carcinomas of the lungs. In addition to cytoplasmic secretory granules best detectable by the method of Grimelius, 7 tumors showed signs of mucus formation. Argyrophil cell carcinomas appear to be poorly differentiated variants of the gastrointestinal tract apudomas.
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