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Central nervous system immunoreactive somatostatin, substance P and metenkephalin concentrations in experimental
Abstract:
Immunoreactive somatostatin, substance P and met-enkephalin concentrations were measured in various regions of the rat brain 65 hours after portacaval shunt and compared with concentrations in sham-operated animals. No significant difference was detected in any of the three peptides in the regions studied, suggesting that these peptides do not play a role ion the pathogenesis of hepatic encephalopathy.