Erythrocyte acetylcholinesterase activity is not affected by adenovirus-induced haemagglutination

No correlation was found between adenovirus-induced haemagglutination and AChE activity of human RBCs as ascertained with three different types of virus. The haemagglutination titre of the adenoviruses did not decrease when RBCs with AChE inhibited by dichlorvos or eserine were used. The receptors involved in active haemagglutination by adenoviruses thus seem to differ from those acting in passive haemagglutination. The AChE inactivating effect of substances such as tannic acid and glutaraldehyde, among others, might be due to a non-specific damage of the RBC membrane.