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Auditory brain stem responses in chronic alcoholic patients.

N S Chu, K C Squires, A Starr

    Electroencephalography and Clinical Neurophysiology
    |October 1, 1982
    PubMed
    Summary

    Chronic alcoholism can cause brain stem abnormalities, detectable by Auditory Brainstem Responses (ABRs). These auditory brain stem response findings correlate with age, neurological complications, and cerebral atrophy in alcoholic patients.

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    Area of Science:

    • Neuroscience
    • Clinical Neurology
    • Audiology

    Background:

    • Chronic alcoholism is associated with significant central nervous system (CNS) damage.
    • Auditory Brainstem Responses (ABRs) are a non-invasive electrophysiological measure of auditory pathway function.
    • Previous studies suggest potential neurological deficits in alcoholic populations.

    Purpose of the Study:

    • To investigate the incidence and characteristics of brain stem abnormalities in chronic alcoholic patients using ABRs.
    • To determine the relationship between ABR abnormalities and factors such as age, neurological complications, and cerebral atrophy.

    Main Methods:

    • Auditory Brainstem Responses (ABRs) were recorded from 66 chronic alcoholic patients.
    • Patients underwent clinical neurological assessment and computerized tomographic (CT) scans.

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  • ABR results were analyzed for prolonged interwave intervals, indicating abnormalities.

    • Main Results:

    • Forty-one percent of alcoholic patients exhibited abnormal ABRs.
    • ABR abnormality incidence increased with patient age and the number of neurological complications.
    • Cerebellar degeneration was associated with the highest ABR abnormality rate (83%).
    • A strong correlation was found between abnormal ABRs and cerebral atrophy observed on CT scans.

    Conclusions:

    • ABRs are a valuable tool for detecting CNS abnormalities in chronic alcoholic patients.
    • The findings highlight the progressive nature of neurological damage in alcoholism.
    • Combined use of ABR and CT scans aids in assessing the extent of CNS involvement.