[Allergic reactions to patent blue violet: mechanisms, frequency and treatment]

The authors report their observation of a serious allergic incident involving the blue patent, hospitalisation in their intensive care unit, and extremely major therapy. They describe the three mechanisms of allergic reaction: real anaphylaxia, and anaphylactoid reaction, either by direct histamino-release, or by alternate activation of the complementary system. It would seem that, after doses of the differing fractions of complement in this patient, there was an activation of the complementary system. The authors emphasize the importance of preventive treatment: hypo-histamine, antihistamine, corticoid, and curative relative to the gravity of the disorders observed: cutaneous, cardiac, and respiratory. Finally, they recall that this test must be carried out in a hospital establishment with a reanimation unit.