Related Experiment Video

Updated: Aug 3, 2026

Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused with Pulsatile Flow
10:02

Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused with Pulsatile Flow

Published on: April 30, 2011

Neuroendocrine and metabolic factors in pulmonary circulatory control

J A Will

    Advances in Shock Research
    |January 1, 1982
    PubMed

    Keywords:
    pulmonary circulationneuroendocrine signalingoxygen exposurevascular adaptation

    More Related Videos

    Isolation of Pulmonary Artery Smooth Muscle Cells from Neonatal Mice08:02

    Isolation of Pulmonary Artery Smooth Muscle Cells from Neonatal Mice

    Published on: October 20, 2013

    Videomorphometric Analysis of Hypoxic Pulmonary Vasoconstriction of Intra-pulmonary Arteries Using Murine Precision Cut Lung Slices13:32

    Videomorphometric Analysis of Hypoxic Pulmonary Vasoconstriction of Intra-pulmonary Arteries Using Murine Precision Cut Lung Slices

    Published on: January 14, 2014

    Related Concept Videos

    Physiological Control of Respiration01:23

    Physiological Control of Respiration

    Introduction
    Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
    Regulation of Ventilation
    The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
    Pathophysiology of Cardiac Performance01:29

    Pathophysiology of Cardiac Performance

    Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
    Autoregulation of Blood Flow01:17

    Autoregulation of Blood Flow

    Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
    Chemical Signaling in Autoregulation
    Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
    Factors Affecting Pulmonary Ventilation01:19

    Factors Affecting Pulmonary Ventilation

    Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
    Alveolar Surface Tension
    The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
    Chemical Factors Affecting Respiration Centers01:31

    Chemical Factors Affecting Respiration Centers

    Chemical factors such as changing CO2, O2, and H+ levels in arterial blood play a critical role in influencing respiration depth and rates. These variations are detected by chemoreceptors—specialized sensors located in two primary body areas. Central chemoreceptors are found throughout the brain stem, including the ventrolateral medulla, while peripheral chemoreceptors are located in the aortic arch and carotid arteries.
    CO2 has a potent influence on respiration and is strictly regulated. Under...
    Physiology of Respiration II: Neurogenic Control of Respiration01:22

    Physiology of Respiration II: Neurogenic Control of Respiration

    The neurogenic control of respiration coordinates various neural networks and pathways to regulate breathing rate and depth, meeting the body's oxygen and carbon dioxide exchange requirements. This system adapts to physiological and environmental conditions, ensuring optimal breathing patterns.
    Central Control
    The brainstem is the primary site of central control, hosting respiratory centers: