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[Specific hyposensitization in allergic diseases (author's transl)].
Deutsche Medizinische Wochenschrift (1946)
|December 23, 1977
Summary
Semi-depot hyposensitization effectively treated 82.4% of patients with allergic manifestations. Treatment success in allergy management is linked to patient age, disease factors, and adherence to allergen immunotherapy schedules.
Area of Science:
- Immunology
- Allergology
Context:
- Allergic manifestations pose a significant health burden.
- Hyposensitization is a key treatment modality for allergies.
Purpose:
- To evaluate the efficacy of semi-depot hyposensitization for allergic manifestations.
- To identify factors influencing treatment success.
Summary:
- Semi-depot hyposensitization achieved an 82.4% efficacy rate in 533 patients.
- Optimal outcomes were associated with younger patients, respiratory tract diseases, short disease duration, single-allergen extracts, limited allergen involvement, prolonged treatment, high final dosage, and strict adherence to schedules.
- Treatment success was independent of patient sex or side effects.
Impact:
- Provides evidence for the effectiveness of semi-depot hyposensitization.
- Offers guidance for optimizing allergen immunotherapy protocols.
- Informs clinical decision-making for allergy treatment.