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Experimental studies on the "cow's urine mixture".

A Grange

    Annals of Tropical Paediatrics
    |September 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Cow's Urine Mixture, a traditional remedy, significantly lowers blood glucose levels in rabbits. This study confirms its hypoglycemic effect via both injection and oral administration.

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    Area of Science:

    • Pharmacology
    • Biochemistry
    • Traditional Medicine

    Background:

    • Cow's Urine Mixture is a traditional remedy used for convulsions.
    • The biochemical and physiological effects of this traditional remedy are not well-understood.
    • Investigating the scientific basis of traditional remedies can offer new therapeutic insights.

    Purpose of the Study:

    • To investigate the hypoglycemic effect of Cow's Urine Mixture.
    • To determine if the route of administration affects the hypoglycemic action.
    • To provide scientific validation for the traditional use of Cow's Urine Mixture.

    Main Methods:

    • Samples of Cow's Urine Mixture were administered to fasting grey rabbits.
    • Administration routes included intraperitoneal injection (parenteral) and nasogastric intubation (enteral).

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  • Plasma glucose levels were measured to assess the hypoglycemic effect.

    • Main Results:

    • Intraperitoneal administration of Cow's Urine Mixture caused significant depression of plasma glucose.
    • Nasogastric administration also resulted in a significant decrease in plasma glucose.
    • The findings confirm a potent hypoglycemic effect regardless of administration route.

    Conclusions:

    • Cow's Urine Mixture possesses a significant hypoglycemic effect.
    • The mixture is effective when administered both parenterally and enterally.
    • Further research is warranted to identify the specific hypoglycemic agents within the mixture.