[Immunologic similarity of antigens of residual nuclear proteins from various hepatomas]

Rabbit antiserum against alkali-insoluble nuclear residual protein of transplantable rat hepatoma 27 reacted with residual proteins during immunodiffusion in agarose gel, provided immunoprecipitation of isolated nuclei and indirect immunofluorescence with Zajdela's rat ascites hepatoma and mouse ascites hepatoma 22a, while the reaction with non-liver tumors--rat Jensen, Yoshida and M 1 sarcomas and mouse Ehrlich ascites carcinoma was negative. Mild indirect immunofluorescence with kidney and spleen sections was eliminated if antiserum was preincubated with acetone powders of these tissues.