[Alpha-2-globulins of blood in experimental burns]

Complex physico-chemical procedures for separation and analysis of protein composition during the separation steps showed that alpha-2-globulins from blood serum of rats with thermic burns differed from the globulins of normal blood serum either in absolute and relative increase in their content or qualitative features: increase in electrophoretic mobility, conformational changes leading to increase in compactness at the slightly acid pH, increase in affinity to anion exchange resin, atypical reactions with a precipitant (rivanol), increase in the rate of dissociation into subunits. The major part of alpha-2-globulins in burns constituted alpha-2-lipoprotein and alpha-2-macroglobulin which were separated with minimal cross-contamination.