Prostatic infiltration in leukaemia and lymphoma.

Area of Science:

• Oncology
• Uropathology

Background:

• Leukemic and lymphomatous infiltration of the prostate is an uncommon finding.
• Previous reports of prostate involvement by lymphoma or leukemia are limited.
• Hodgkin's disease has not been previously reported to involve the prostate.

Purpose of the Study:

• To report 12 cases of prostate infiltration by leukemia or lymphoma.
• To highlight the diagnostic challenges and histological confirmation.
• To discuss the management of prostatic leukemic and lymphomatous infiltration.

Main Methods:

• Retrospective review of 12 cases with prostate leukemic or lymphomatous infiltration.
• Histological examination of prostate specimens for diagnosis.
• Analysis of clinical presentation, preoperative diagnosis, and postmortem findings.

Main Results:

• Twelve cases of prostate infiltration by leukemia or lymphoma were identified.
• One case of Hodgkin's disease involving the prostate was observed.
• Histological diagnosis was confirmed in all cases.
• Preoperative diagnoses included benign prostatic hypertrophy and prostatic carcinoma.
• In 6 patients, leukemia or lymphoma was diagnosed from the prostatic specimen.
• In one case, infiltration was discovered postmortem.

Conclusions:

• Prostate infiltration by leukemia and lymphoma can mimic other prostatic diseases.
• Histological examination is crucial for accurate diagnosis.
• Management strategies for these rare infiltrations require consideration.