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Initial experience with universal pacemakers.

J Duncan, B S Goldman, A W Chisholm

    Pacing and Clinical Electrophysiology : PACE
    |July 1, 1983
    PubMed
    Summary
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    This study evaluated the Sequicor DDD pacemaker in 35 patients, finding high battery drain but improved hemodynamic benefits in 70% compared to older pacing modes.

    Area of Science:

    • Cardiology
    • Biomedical Engineering
    • Medical Device Technology

    Background:

    • Dual-chamber pacing (DDD) offers potential hemodynamic advantages over single-chamber modes (DVI, VVI).
    • Early evaluation of novel pacemaker systems is crucial for understanding performance and patient outcomes.

    Purpose of the Study:

    • To assess the initial clinical performance and patient outcomes of the Sequicor DDD pacemaker.
    • To compare the hemodynamic benefits of DDD pacing with DVI or VVI pacing.

    Main Methods:

    • Implantation of the Sequicor DDD pacemaker in 35 patients (mean age 61.7 years) between September 1981 and March 1982.
    • Patient stratification into two groups based on ECG: A-V block and sick sinus syndrome.
    • Evaluation of electronic component function, battery drain, complications, and hemodynamic effects.

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    Main Results:

    • Excellent electronic component function was observed, with one exception (reed switch).
    • High battery drain was noted with the Sequicor device.
    • Complications were similar to those associated with DVI or VVI pacing.
    • Seventy percent of patients demonstrated increased hemodynamic benefits with DDD pacing compared to DVI or VVI.

    Conclusions:

    • The Sequicor DDD pacemaker shows promise for improving hemodynamic function in a majority of patients.
    • Despite challenges like battery drain, DDD pacing offers significant advantages over single-chamber pacing modes.
    • Further investigation into battery longevity and complication profiles is warranted for long-term DDD pacemaker use.