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[Various pathogenetic mechanisms of ischemic stroke in cardiac rhythm disorders]

R A Aristova, N V Kazantseva

    Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952)
    |January 1, 1983
    PubMed

    Insights

    Ischemic stroke patients show a direct link between brain activity changes and overall blood flow issues. This connection suggests impaired vascular tone autoregulation, particularly near the stroke site, impacts cerebral function.

    Area of Science:

    • Neurology
    • Cardiology
    • Biomedical Engineering

    Background:

    • Ischemic stroke often co-occurs with cardiac rhythm disturbances.
    • Understanding the interplay between cerebral and hemodynamic changes is crucial for stroke management.

    Observation:

    • Polygraphic examinations (EEG, ECG, sphygmograms, phlebograms) were performed on 60 ischemic stroke patients and 30 healthy controls.
    • Data analyzed included electroencephalograms (EEGs), electrocardiograms (ECGs), temporal artery sphygmograms, and jugular vein phlebograms.

    Findings:

    • A direct relationship was observed between the severity of cerebral bioelectric activity alterations and the intensity of general hemodynamic disorders in ischemic stroke patients.
    • These findings suggest that disrupted vascular tone autoregulation, especially on the side of the ischemic focus, contributes to the observed changes.

    Implications:

    • The study highlights the interconnectedness of neurological and cardiovascular systems in ischemic stroke.
    • Results may inform diagnostic and therapeutic strategies targeting vascular autoregulation in stroke patients.

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