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Multiple sclerosis with onset after age 60
Journal of the American Geriatrics Society
|January 1, 1984
Summary
Late-onset multiple sclerosis (MS) is rare, often delaying diagnosis in older adults. Early consideration and specific tests can aid in identifying MS in this population.
Area of Science:
- Neurology
- Geriatrics
- Immunology
Background:
- Multiple sclerosis (MS) onset typically occurs in younger adults.
- MS after age 60 is exceptionally rare, posing diagnostic challenges.
Observation:
- Three cases of late-onset MS (onset >60 years) are presented.
- Symptoms were initially misattributed to common geriatric conditions.
- Diagnostic delays were significant in all reported cases.
Findings:
- Clinical presentation of late-onset MS can mimic other age-related diseases.
- Cerebral evoked potentials and CSF immunoglobulin studies can aid diagnosis.
- MS should be considered in the differential diagnosis of elderly patients with neurological symptoms.
Implications:
- Increased awareness of late-onset MS is crucial for timely diagnosis.
- Utilizing specific neurophysiological and immunological tests can improve diagnostic accuracy.
- Prompt MS diagnosis in older adults can lead to earlier treatment and better management.