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Antigen-induced histamine-release in diagnosis of allergy
Allergie Und Immunologie
|January 1, 1983
Abstract:
Antigen-induced histamine-release from basophils was evaluated in 12 patients with hypersensitivity to grass, 14 patients with hypersensitivity to grains and 14 patients with hypersensitivity to insect-venom using a test with very high sensitivity. - Histamine-release upon stimulation with antigen was found in all patients with grass-hypersensitivity, in 12 of 14 patients with grain-hypersensitivity and in 10 of 14 patients with insect-venom-hypersensitivity. Additionally performed determination of total-IgE proved less valuable, whereas specific-IgE and skin-test showed a higher validity in hypersensitivity to grains.