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Pulmonary resection in metastatic carcinoma.
Chest
|February 1, 1978
Summary
Surgical removal of pulmonary metastases from various carcinomas can achieve survival rates comparable to those seen in osteogenic sarcoma. This approach is effective when specific patient criteria are met, offering a viable treatment option.
Area of Science:
- Surgical Oncology
- Thoracic Surgery
- Cancer Metastasis
Background:
- Previous studies reported 5-year survival rates of 27% for osteogenic sarcoma pulmonary metastases and 26% for all sarcomas.
- Pulmonary metastases from carcinomas have historically presented a challenge for surgical intervention.
Purpose of the Study:
- To evaluate the efficacy of surgical resection for pulmonary metastases originating from various carcinomas.
- To determine if similar survival rates to those seen in sarcomas can be achieved in carcinoma patients.
Main Methods:
- Review of 188 patients who underwent 242 thoracotomies for pulmonary metastases from carcinomas.
- Analysis of patient data focusing on primary cancer site, surgical outcomes, and survival rates.
Main Results:
- Surgical excision of pulmonary metastases from carcinomas demonstrated a comparable five-year survival rate to that of sarcomas.
- Most frequent primary sites included colon, melanoma, breast, and testicular carcinoma.
- Successful surgical management was achieved in 188 patients.
Conclusions:
- Surgical resection of pulmonary metastases from carcinomas is a justifiable treatment modality.
- Treatment is recommended when the primary tumor is controlled, no extrapulmonary metastases exist, the patient is a good surgical risk, and no effective non-surgical options are available.