[Use of the pneumococcal serovar 3 erythrocyte antibody diagnostic agent for analyzing polysaccharide-containing...

Antibody diagnosticum to pneumococci (serovar 3) has been prepared. The analysis of different antigenic preparations of pneumococci (serovars 1,3 and 6B) and the filtrates of culture fluid obtained in the process of the cultivation of bacteria belonging to serovars 3,9N and 23F has been carried out by means of the indirect hemagglutination test. The new diagnosticum has proved to be type-specific. This diagnosticum can be used for the evaluation of the quantitative content of specific polysaccharide in different antigenic preparations of serovar 3 pneumococci, as well as for the determination of the content of specific polysaccharide directly in the culture fluid, which constitutes a step in the determination of the period of the maximum synthesis of polysaccharide, necessary for the optimization of the process of the cultivation of pneumococci.